CYSTIC FIBROSIS web quest

CYSTIC FIBROSIS - A DISORDER OF MEMBRANE TRANSPORT

A great variety of proteins have roles in moving molecules and ions across cell membranes. Passive transport proteins permit certain substances to diffuse down concentration gradients by moving through the protein's interior. Active transport proteins use ATP energy to pump substances across the membrane against their concentration gradients. To investigate the importance of transport proteins, we will consider the effects of cystic fibrosis, a genetic disorder in which there is a defect in a transport protein..

Activity

Part 1.

In this part of the activity you will visit the Cystic Fibrosis Foundation’s web site to learn about the causes and symptoms of cystic fibrosis.

Use your browser to go to http://www.cff.org/home/

Use the information provided in the “About cystic fibrosis” section to answer the following questions:

1. What are the signs and symptoms of cystic fibrosis?

Very salty tasty skin. Wheezing and shortness of breath.

2. How common is this disorder?

The disorder is not that common. Only 30,000 people in america and 70,000 world wide.

3. How is cystic fibrosis diagnosed?

By a fat protein that is no good. It causes thick mucus in your lungs and digestive system.

4. How is cystic fibrosis inherited? Does everyone who has a mutant gene for the protein have cystic fibrosis?

Its a fallen protein gene. Yes everyone who has a the protein has cf

Part 2.

In this part of the activity you will read an article to learn more about cystic fibrosis.

Use your browser to go to:

http://resources.schoolscience.co.uk/MRC/3/page3.html

Use the information in this article to answer the following questions:

1. Explain the normal function of the protein that is defective in cystic fibrosis.

poorly permeable to chloride ions

2. What happens to this protein in CF patients and what are the consequences for the health of these individuals?

The channel is blocked

Part 3.

In this part of the activity you will read about how cystic fibrosis is treated.

Use your browser to go to:

http://www.mayoclinic.com/health/cystic-fibrosis/DS00287

Use the information in the different sections of the article to answer the following questions:

1. Explain at least 3 treatments for the symptoms of cystic fibrosis.

You get breathless, wheezing, and repeated lung infections.

2. Discuss at least 3 ways for parents to help their children who have cystic fibrosis.

Join a club that has meetings that help explain their problems, have them eat extra salt in hot weather, and don't smoke.

lab report for the diffusion lab

Questions: 

Q1:how would you explain the results you optioned? which substance(s) are entering the bag and which are leaving the bag?  support your answer with experimental evidence.

A1:the subtance entering the bah is iidim because the solution on the inside changed colors. witch turned the water clear. the glucose exited the bag because the water tested positive with the glucose test stripe

Q2:what evidence could have been collected to show quantitatively that water diffused tin no the dialysis bag?

A2:the bag had little tiny holes that water could get in here and resolve th molecules in the bag and beaker.

Q3:what result would you expcet if the experiment started with a glucose and IKI solution inside the bag and only starch and water outside?WHY? 

A3:i don't now what would happen  i think the results would be opposite then what we seen before.

Procedure:

1. fill a 8-oz cup two-thireds full with distilled water. add approximately 4 ml of IKI to the distilled water, mix well  and record the color of the solution in table 1.1. test this solution with a clucose indicator strip and record the results in table 1.1. 
2. test the 15% glucose/1% starch solution with a glucose indicator strip. record the resutlts in table1.1.
3. obtain a 30-cm piece of 2.5-cm dialysis tubing that has been soaking in water. tie off one end of the tubing to form a bag. to open the other end to the bag, rub the end between your fingers until the edges separate.
4.using a small funnel, place 15ml of the 15% glucose/1% starch solution in the bag. tie off the other end of the bag, leaving about 4 cm between the solution and the end of the bag so the contents of the bag can expand. record to color of the solution tin table 1.1.

Evidence: